[Oral contraceptives and endometrial and ovarian carcinomas].

Abstract

Combined oral contraceptives reduce the risk of endometrial and ovarian cancer by about 50%. The risk of both carcinomas decreases with an increasing duration of oral contraceptive use. The reduced risk lasts for 10-15 years after cessation. A significantly lower risk of developing an endometrial carcinoma can be observed for contraceptives with a high progestin and a low estrogen concentration. Due to the protective effect, the use of oral contraceptives is a useful means for primary prevention (chemoprevention) in women at high risk of endometrial and ovarian cancers.

• Authors: M Medl
• Journal: Gynakologisch-geburtshilfliche Rundschau (Gynakol Geburtshilfliche Rundsch) Vol. 38 Issue 2 Pg. 105-8 ( 1998) ISSN: 1018-8843 [Print] Switzerland
• Vernacular Title: "Pille" und Endometrium-sowie Ovarialkarzinome.
• PMID: 9815528 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Contraceptives, Oral, Combined

Topics

• Contraceptives, Oral, Combined (administration & dosage, adverse effects)
• Dose-Response Relationship, Drug
• Endometrial Neoplasms (prevention & control)
• Female
• Humans
• Ovarian Neoplasms (prevention & control)
• Risk