Folliculitis spinulosa decalvans: successful therapy with dapsone.

Abstract

A 27-year-old male patient presented with scaly erythema and crusts on the scalp. Since birth, he suffered from dry skin and inflammation of the eyelids. Scarring alopecia was noticed in some regions of his scalp. Folliculitis spinulosa decalvans was diagnosed. Therapy with isotretinoin and topical corticosteroids was without effect. In contrast, 100 mg of Dapsone per day led to resolution of the inflammatory signs. This enabled him to cover the disfiguring scarring alopecia with a permanent hairpiece. His condition has been stable after 18 months without the enlargement of the scarred alopecic areas.

• Authors: C Kunte, C Loeser, H Wolff
• Journal: Journal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 39 Issue 5 Pt 2 Pg. 891-3 (Nov 1998) ISSN: 0190-9622 [Print] United States
• PMID: 9810924 (Publication Type: Case Reports, Journal Article)

Chemical References

• Adrenal Cortex Hormones
• Anti-Inflammatory Agents, Non-Steroidal
• Keratolytic Agents
• Dapsone
• Isotretinoin

Topics

• Adrenal Cortex Hormones (therapeutic use)
• Adult
• Alopecia (drug therapy)
• Anti-Inflammatory Agents, Non-Steroidal (therapeutic use)
• Blepharitis (congenital)
• Cicatrix (drug therapy)
• Dapsone (therapeutic use)
• Erythema (drug therapy)
• Folliculitis (drug therapy)
• Follow-Up Studies
• Humans
• Isotretinoin (therapeutic use)
• Keratolytic Agents (therapeutic use)
• Male
• Scalp Dermatoses (drug therapy)
• Skin Diseases (congenital)
• Treatment Outcome