Abstract | OBJECTIVES: METHODS: RESULTS: Twenty of the 24 patients had an average of 1.4 episodes of abnormal liver function tests associated with biliary colic; eight patients had dilated common bile duct on cholangiogram. Eighteen of the 20 patients with abnormal liver function tests (90%) were pain-free after sphincterotomy; in contrast, only one of four patients (25%) without liver function test changes responded to sphincterotomy. Fisher exact analysis showed that abnormal liver function tests was a significant predictor for favorable response to sphincterotomy with a two-tail p value of 0.018. Of the eight patients with bile duct dilatation, six (75%) responded favorably to sphincterotomy, whereas 13 of 16 patients (81%) without dilatation also responded to sphincterotomy. Analysis of common bile duct dilatation as a predictive factor showed no significance (p=1.00). CONCLUSIONS: We conclude that the occurrence of abnormal liver function tests during biliary colic may be used to select patients for endoscopic sphincterotomy. Sphincter of Oddi manometry may not be needed in these cases.
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Authors | O S Lin, R M Soetikno, H S Young |
Journal | The American journal of gastroenterology
(Am J Gastroenterol)
Vol. 93
Issue 10
Pg. 1833-6
(Oct 1998)
ISSN: 0002-9270 [Print] United States |
PMID | 9772040
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Case-Control Studies
- Cholecystectomy
- Colic
(physiopathology, surgery)
- Common Bile Duct Diseases
(physiopathology, surgery)
- Female
- Humans
- Liver Function Tests
- Male
- Manometry
- Middle Aged
- Patient Selection
- Postoperative Complications
(physiopathology, surgery)
- Predictive Value of Tests
- Retrospective Studies
- Sphincter of Oddi
(physiopathology)
- Sphincterotomy, Endoscopic
- Treatment Outcome
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