[A patient with disopyramide intoxication rescued by percutaneous cardiopulmonary support].

Abstract

A 28-year-old man was admitted to our hospital in a hypotensive state 2 hours after taking 8,400 mg disopyramide. Infusion of catecholamine and gastric lavage restored normal blood pressure. However, 8 hours after taking the disopyramide he became hypotensive again and electrocardiographic findings revealed bizarre ventricular complexes resulting in ventricular flutter. Although standard cardiopulmonary resuscitation was not effective, his circulatory status was maintained by percutaneous cardiopulmonary support (PCPS). After 36 hours electrocardiography showed sinus rhythm, and his cardiac function became normal. Patients with severe cardiac dysfunction or cardiac arrest caused by disopyramide intoxication can be supported by PCPS until cardiac function is restored.

• Authors: K Yoshida, K Kimura, K Hibi, T Nemoto, Y Iwasawa, Y Hongo, M Sugiyama, T Ishikawa, N Kuji, O Tochikubo, M Ishii
• Journal: Journal of cardiology (J Cardiol) Vol. 32 Issue 2 Pg. 95-100 (Aug 1998) ISSN: 0914-5087 [Print] Netherlands
• PMID: 9752618 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Anti-Arrhythmia Agents
• Disopyramide

Topics

• Adult
• Anti-Arrhythmia Agents (poisoning)
• Arrhythmias, Cardiac (chemically induced)
• Assisted Circulation
• Disopyramide (poisoning)
• Humans
• Hypotension (chemically induced)
• Intra-Aortic Balloon Pumping
• Male
• Poisoning (therapy)