Abstract | OBJECTIVE: METHODS: RESULTS: In all patients, pruritus ceased completely and bilirubin returned to normal values. The symptoms recurred after rifampicin withdrawal on, at least, three occasions in each patient, and these symptoms were always eliminated after its reintroduction. The patients had a total of 16 cholestatic episodes during a follow-up of 8 yr, with a complete clinical recovery in all of them. Undergoing therapy with a suitable dosage of rifampicin, none of the patients had a cholestatic crisis even during a period for as long as 12 months. The diagnosis of two patients was consistent with benign recurrent intrahepatic cholestasis, and it was not well defined in the remaining. CONCLUSION:
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Authors | E L Cançado, R M Leitão, F J Carrilho, A A Laudanna |
Journal | The American journal of gastroenterology
(Am J Gastroenterol)
Vol. 93
Issue 9
Pg. 1510-7
(Sep 1998)
ISSN: 0002-9270 [Print] United States |
PMID | 9732934
(Publication Type: Case Reports, Journal Article)
|
Chemical References |
- Cholagogues and Choleretics
- gamma-Glutamyltransferase
- Rifampin
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Topics |
- Adult
- Child, Preschool
- Cholagogues and Choleretics
(therapeutic use)
- Cholestasis, Intrahepatic
(drug therapy, enzymology)
- Family Health
- Female
- Humans
- Pruritus
(drug therapy)
- Recurrence
- Remission Induction
- Rifampin
(therapeutic use)
- gamma-Glutamyltransferase
(blood)
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