A putative human papillomavirus type 57 new subtype isolated from plantar epidermoid cysts without intracytoplasmic inclusion bodies.

Abstract

Human papillomavirus type 60 (HPV-60) is the only virus type that has been identified in epidermoid cysts. In this study, HPV-57 DNA was found in three out of 18 plantar epidermoid cysts with different histological features from HPV-60-associated cysts, using PCR and Southern hybridization. The HPV-57-associated cysts had features resembling an HPV-2-specific cytopathic effect. The sequences of two HPV-57 DNA clones isolated from two patients were identical, but differed at some positions from those of HPV-57a and HPV-57b. This putative new subtype was tentatively designated as HPV-57c, and may be associated with plantar epidermoid cysts showing histological features resembling the HPV-2 cytopathic effect.

• Authors: H Kitasato, K Egawa, Y Honda, T Ono, Y Mizushima, S Kawai
• Journal: The Journal of general virology (J Gen Virol) Vol. 79 ( Pt 8) Pg. 1977-81 (Aug 1998) ISSN: 0022-1317 [Print] England
• PMID: 9714246 (Publication Type: Journal Article)

Chemical References

• DNA, Viral

Topics

• Amino Acid Sequence
• Base Sequence
• DNA, Viral
• Epidermal Cyst (pathology, virology)
• Foot Diseases (pathology, virology)
• Humans
• Inclusion Bodies, Viral
• Molecular Sequence Data
• Papillomaviridae (classification, genetics, isolation & purification)