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Methotrexate for resistant chronic uveitis in children with juvenile rheumatoid arthritis.

Abstract
We used low-dose methotrexate to treat seven children with juvenile rheumatoid arthritis-associated uveitis complicated by cataract and glaucoma or resistant to topical corticosteroid. The use of methotrexate decreased the severity of uveitis in six of seven patients and allowed for the discontinuation or reduction of corticosteroid drops.
AuthorsA H Weiss, C A Wallace, D D Sherry
JournalThe Journal of pediatrics (J Pediatr) Vol. 133 Issue 2 Pg. 266-8 (Aug 1998) ISSN: 0022-3476 [Print] United States
PMID9709718 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antirheumatic Agents
  • Immunosuppressive Agents
  • Methotrexate
Topics
  • Adolescent
  • Adult
  • Antirheumatic Agents (therapeutic use)
  • Arthritis, Juvenile (complications, drug therapy)
  • Child
  • Child, Preschool
  • Chronic Disease
  • Female
  • Humans
  • Immunosuppressive Agents (therapeutic use)
  • Methotrexate (therapeutic use)
  • Treatment Outcome
  • Uveitis (complications, drug therapy)

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