[Clinical and laboratory study of cefodizime (Modivid) in prophylaxis and treatment of surgical patients].

Abstract

The results of the clinical and laboratory study of the efficacy of the prophylactic and therapeutic use of cefodizime (modivid) in patients with chronic calculous cholecystitis and burns are presented. Expediency of the preoperative prophylactic use of the drug and its significance in the treatment of infectious complications of the burn disease were verified. The immunological investigation gave evidence of an increase of the phagocytosis functional activity when cefodizime (modivid) was used prophylactically in cholecystectomy.

• Authors: E P Khlebnikov, V P Iakovlev, L V Elagina, V A Kubyshkin, M G Krutikov, M V Pavlova, I A Grishina, A A Alekseev, A I Kurochkina
• Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] (Antibiot Khimioter) Vol. 43 Issue 6 Pg. 16-9 ( 1998) ISSN: 0235-2990 [Print] Russia (Federation)
• Vernacular Title: Kliniko-laboratornaia otsenka tsefodizima (modivida) pri profilakticheskom i lechebnom primenenii v khirurgii.
• PMID: 9644529 (Publication Type: Clinical Trial, Controlled Clinical Trial, English Abstract, Journal Article)

Chemical References

• Cephalosporins
• Cefotaxime
• cefodizime

Topics

• Adolescent
• Adult
• Aged
• Antibiotic Prophylaxis
• Antibody Formation (drug effects)
• Burns (drug therapy, immunology, microbiology)
• Cefotaxime (administration & dosage, analogs & derivatives, therapeutic use)
• Cephalosporin Resistance
• Cephalosporins (administration & dosage, therapeutic use)
• Cholecystitis (complications, immunology, surgery)
• Cholelithiasis (complications, immunology, surgery)
• Colony Count, Microbial
• Humans
• Immunity, Cellular (drug effects)
• Male
• Middle Aged
• Surgical Wound Infection (immunology, microbiology, prevention & control)