Patients with Hashimoto's disease treated with L-thyroxine and followed for three years.

Abstract

This study investigated the effectiveness of L-thyroxine management in 32 patients (mean age 11 years and 2 months; M:F = 1:5) with Hashimoto's disease followed annually for 3 years. One (8%) of the 12 patients, euthyroid at the onset, never required treatment; of the four (33%) who began treatment immediately, two were able to stop at the 1st or 2nd follow-up, whereas two had to continue. The other seven (59%) who did not begin treatment immediately had to start at the 1st, 2nd or 3rd follow-up. The findings in this small series suggest that hormone management may prove effective to a certain extent in euthyroid Hashimoto patients, primarily as a means of prevention.

• Authors: G C Mussa, A Corrias, M Mostert, D Pellegrino, L Silvestro
• Journal: Journal of pediatric endocrinology & metabolism : JPEM (J Pediatr Endocrinol Metab) 1998 Jan-Feb Vol. 11 Issue 1 Pg. 59-62 ISSN: 0334-018X [Print] Germany
• PMID: 9642630 (Publication Type: Clinical Trial, Journal Article)

Chemical References

• Thyroxine

Topics

• Adolescent
• Child
• Female
• Follow-Up Studies
• Humans
• Male
• Thyroiditis, Autoimmune (drug therapy)
• Thyroxine (therapeutic use)