Abstract | BACKGROUND: Although the distinction between clonal and reactive thrombocytosis is clinically relevant because clonal thrombocytosis has more thrombohemorragic complications, the differential diagnosis of these two entities can be difficult. Methods such as the detection of unstimulated erythroid or megakaryocyte colony growth are not readily available. Therefore, we measured blood thrombopoietin levels to determine whether these levels can be used to distinguish the two conditions. PATIENTS AND METHODS: RESULTS: CONCLUSIONS:
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Authors | J C Wang, C Chen, A D Novetsky, S M Lichter, F Ahmed, N M Friedberg |
Journal | The American journal of medicine
(Am J Med)
Vol. 104
Issue 5
Pg. 451-5
(May 1998)
ISSN: 0002-9343 [Print] United States |
PMID | 9626028
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Anemia, Iron-Deficiency
(complications)
- Anemia, Sickle Cell
(complications)
- Case-Control Studies
- Diagnosis, Differential
- Female
- Humans
- Inflammation
(complications)
- Male
- Middle Aged
- Neoplasms
(complications)
- Platelet Count
- Polycythemia Vera
(complications)
- Primary Myelofibrosis
(complications)
- Reproducibility of Results
- Thrombocythemia, Essential
(complications)
- Thrombocytosis
(blood, classification, diagnosis, etiology)
- Thrombopoietin
(blood)
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