[Thiamine deficit in acute alcoholic psychoses].

Abstract

In 35 females and 22 males with acute alcoholic disorders and in 44 individuals of a control group the author studied the indices of thiamine balance--the content of thiamine and pyruvic acid in the blood and urine, concentration of citric acid in the blood, activity of transketolase of erythrocytes and TDP-effect. The results demonstrated that a thiamide deficiency in excretion and insufficiency in coenzyme functions of oxidative decarboxylation of pyruvic acid and in the pentose cycle is seen not only in alcoholic psychoses, but in the withdrawal syndrome. Sex differences of these indices and their development were not noted. It is assumed that the clinical traits of alcoholic disorders in females are not related to changes in the thiamine metabolism.

• Authors: Iu A Mileĭkovskiĭ
• Journal: Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952) (Zh Nevropatol Psikhiatr Im S S Korsakova) Vol. 76 Issue 7 Pg. 1074-9 ( 1976) ISSN: 0044-4588 [Print] Russia (Federation)
• Vernacular Title: Defitsit tiamina pri ostrykh alkogol'nykh psikhozakh
• PMID: 961293 (Publication Type: English Abstract, Journal Article)

Chemical References

• Citrates
• Pyruvates
• Transketolase
• Thiamine

Topics

• Acute Disease
• Citrates (metabolism)
• Erythrocytes (enzymology)
• Female
• Humans
• Male
• Psychoses, Alcoholic (enzymology, etiology, metabolism)
• Pyruvates (metabolism)
• Sex Factors
• Substance Withdrawal Syndrome (metabolism)
• Thiamine (metabolism)
• Thiamine Deficiency (complications)
• Transketolase (metabolism)