Abstract | OBJECTIVE: METHOD AND MATERIALS: A split-mouth design was used so that each patient received all treatments simultaneously. Randomly selected quadrants were treated with application of 25% metronidazole gel, subgingival scaling, or a combination of scaling and gel application. The remaining quadrant in each patient was left untreated as a control. RESULTS: All three treatments were effective in significantly reducing Plaque Index, Gingival Index, and bleeding on probing over the 14-week observation period. No statistically significant differences were found between scaling alone and combined treatment. Scaling and combined treatment were better than metronidazole. Metronidazole produced transient effects, best noted during the first 4 weeks after treatment. No additive effect of metronidazole was noted in the combined treatment. At week 14, only combined treatment sites and scaled sites showed statistically greater probing depth reduction than control sites. CONCLUSION:
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Authors | F A Awartani, B J Zulqarnain |
Journal | Quintessence international (Berlin, Germany : 1985)
(Quintessence Int)
Vol. 29
Issue 1
Pg. 41-8
(Jan 1998)
ISSN: 0033-6572 [Print] Germany |
PMID | 9611474
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Review)
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Chemical References |
- Anti-Bacterial Agents
- Antitrichomonal Agents
- Gels
- Metronidazole
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Topics |
- Adult
- Analysis of Variance
- Anti-Bacterial Agents
(administration & dosage, therapeutic use)
- Antitrichomonal Agents
(administration & dosage, therapeutic use)
- Dental Plaque
(prevention & control)
- Dental Plaque Index
- Dental Scaling
- Gels
- Humans
- Male
- Metronidazole
(administration & dosage, therapeutic use)
- Middle Aged
- Periodontal Index
- Periodontitis
(drug therapy, therapy)
- Single-Blind Method
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