Abstract |
The Walker carcinosarcoma cells were cultured in the medium with low concentration (0.25%) of fetal calf serum, in the presence of native or methylamine-treated (modified) human alpha 2-macroglobulin (alpha 2-MG) in vitro. The proliferative activity (3H-thymidine incorporation) of these cells increased in the presence of one or the other alpha 2-MG preparation. It allows to suppose that the human alpha 2-MG may serve as a growth-stimulating factor of tumour cells.
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Authors | N V Mal'tseva, S V Arkhipova, N A Zorin |
Journal | Tsitologiia
(Tsitologiia)
Vol. 40
Issue 2-3
Pg. 167-71
( 1998)
ISSN: 0041-3771 [Print] Russia (Federation) |
Vernacular Title | Vliianie alpha2-makroglobulina cheloveka na proliferativnuiu opukholevykh kletok krys] |
PMID | 9610481
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Methylamines
- alpha-Macroglobulins
- methylamine
|
Topics |
- Animals
- Carcinosarcoma
(pathology)
- Cell Division
(drug effects)
- Humans
- Methylamines
(chemistry)
- Rats
- Tumor Cells, Cultured
- alpha-Macroglobulins
(chemistry, pharmacology)
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