Abstract | PURPOSE: SETTING: Department of Ophthalmology, Hospital Capuchos, Lisbon, Portugal. METHODS: This prospective, randomized controlled study comprised 59 eyes. Thirty-one eyes had phacoemulsification (in-the-bag cracking technique) under topical anesthesia with anterior chamber irrigation by preservative-free lidocaine 1%. Twenty-eight eyes having the same procedure but with local- regional anesthesia served as the control group. All eyes had preoperative and postoperative specular microscopy and computer-assisted morphometry. A Student's t-test was used for between-group comparison of the following parameters: patient age, central corneal endothelial cell loss, mean endothelial cell size variation, and phacoemulsification ultrasound time Follow-up was 4 weeks. RESULTS: The between-group differences in mean patient age and ultrasound time were not significant. The differences between groups in the endothelial cell parameters were also not significant. Mean postoperative endothelial cell loss was 3.59% +/- 2.79 (SD) in the topical anesthesia group and 4.37 +/- 2.00% in the control group. Mean variation in cell size was 3.71 +/- 1.57% and 3.79 +/- 1.07%, respectively. CONCLUSION:
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Authors | A Garcia, F Loureiro, A Limão, A Sampaio, J Ilharco |
Journal | Journal of cataract and refractive surgery
(J Cataract Refract Surg)
Vol. 24
Issue 3
Pg. 403-6
(Mar 1998)
ISSN: 0886-3350 [Print] United States |
PMID | 9580374
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Adjuvants, Anesthesia
- Anesthetics, Local
- Ophthalmic Solutions
- Preservatives, Pharmaceutical
- Procaine
- Lidocaine
- benoxinate
- Bupivacaine
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Topics |
- Adjuvants, Anesthesia
(administration & dosage)
- Aged
- Anesthesia, Local
(methods)
- Anesthetics, Local
(administration & dosage)
- Anterior Chamber
(drug effects)
- Bupivacaine
(administration & dosage)
- Cell Count
- Drug Evaluation
- Endothelium, Corneal
(drug effects)
- Humans
- Lens Implantation, Intraocular
- Lidocaine
(administration & dosage)
- Ophthalmic Solutions
- Phacoemulsification
- Preservatives, Pharmaceutical
- Procaine
(administration & dosage, analogs & derivatives)
- Prospective Studies
- Therapeutic Irrigation
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