HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Carcinoma of the uterine cervix. High-resolution turbo spin-echo MR imaging with contrast-enhanced dynamic scanning and T2-weighting.

AbstractPURPOSE:
To compare high-resolution contrast-enhanced (Gd-DTPA) dynamic MR imaging with T2-weighted turbo spin-echo (TSE) imaging in the evaluation of uterine cervical carcinoma.
MATERIAL AND METHODS:
Thirty-two patients with cervical carcinoma underwent MR imaging on a 1.5 T superconductive unit to have the extension of the disease assessed before treatment. A phased-array coil was used in all patients. In 25 patients, surgical confirmation of the diagnosis was obtained after imaging. Radiation therapy was selected for the remaining 7 patients with advanced carcinoma. Qualitative and quantitative image analyses were also performed.
RESULTS:
The cervical carcinomas showed maximum contrast in the cervical stroma and myometrium in the early dynamic phase. The tumor/cervical-stroma contrast in the early dynamic phase obtained with the T1-weighted TSE technique (contrast-to-noise ratio 22.6) was significantly higher than that obtained in T2-weighted TSE imaging (contrast-to-noise ratio 4.3). In the evaluation of parametrial invasion, the accuracy of T2-weighted imaging was 71.8% and contrast-enhanced dynamic imaging 81.2%.
CONCLUSION:
High-resolution contrast-enhanced (Gd-DTPA) dynamic MR imaging in cervical cancer offers improved tumor/cervical-stroma contrast and provides useful information on parametrial invasion.
AuthorsY Abe, Y Yamashita, T Namimoto, M Takahashi, H Katabuchi, N Tanaka, H Okamura
JournalActa radiologica (Stockholm, Sweden : 1987) (Acta Radiol) Vol. 39 Issue 3 Pg. 322-6 (May 1998) ISSN: 0284-1851 [Print] England
PMID9571952 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Gadolinium DTPA
Topics
  • Adult
  • Aged
  • Carcinoma (diagnosis, pathology)
  • Female
  • Gadolinium DTPA
  • Humans
  • Magnetic Resonance Imaging (methods)
  • Middle Aged
  • Uterine Cervical Neoplasms (diagnosis, pathology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: