Metipranolol-associated nongranulomatous anterior uveitis.

Abstract

PURPOSE:

To describe the findings in a patient with a nongranulomatous anterior uveitis, presumed to be induced by metipranolol.

METHOD:

A 69-year-old woman developed bilateral, nongranulomatous, anterior uveitis while undergoing treatment with metipranolol 0.3% for primary open-angle glaucoma. Four months after resolution of the initial episode, the patient was challenged with metipranolol 0.3% in the right eye.

RESULT:

On reinstituting metipranolol 0.3%, the patient once again developed a unilateral, nongranulomatous, anterior uveitis in the challenged eye.

CONCLUSION:

Metipranolol 0.3% eyedrops, used to treat primary open-angle glaucoma, appear to cause a nongranulomatous anterior uveitis.

• Authors: N P Patel, K H Patel, M R Moster, G L Spaeth
• Journal: American journal of ophthalmology (Am J Ophthalmol) Vol. 123 Issue 6 Pg. 843-4 (Jun 1997) ISSN: 0002-9394 [Print] United States
• PMID: 9535634 (Publication Type: Case Reports, Journal Article)

Chemical References

• Adrenergic beta-Antagonists
• Ophthalmic Solutions
• Metipranolol

Topics

• Adrenergic beta-Antagonists (adverse effects, therapeutic use)
• Aged
• Female
• Glaucoma, Open-Angle (drug therapy)
• Granuloma (chemically induced)
• Humans
• Intraocular Pressure
• Metipranolol (adverse effects, therapeutic use)
• Ophthalmic Solutions
• Recurrence
• Uveitis, Anterior (chemically induced)
• Visual Acuity