HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Percutaneous CT-guided catheter drainage of infected acute necrotizing pancreatitis: techniques and results.

AbstractOBJECTIVE:
The objective of this paper was to assess the safety and efficacy of percutaneous catheter drainage for initial treatment of infected acute necrotizing pancreatitis.
MATERIALS AND METHODS:
Thirty-four patients with acute necrotizing pancreatitis shown with contrast-enhanced CT were treated for sepsis with percutaneous catheter drainage. Extent of necrosis was less than 30% in 10 cases, 30-50% in 10 cases, and greater than 50% in 14 cases. Fourteen patients had central necrosis. Eighteen patients were critically ill with multiorgan failure.
RESULTS:
Sixteen (47%) of the 34 patients were cured with only percutaneous catheter drainage, including four (29%) of the 14 patients with central gland necrosis and 12 (60%) of the 20 with body-tail necrosis. Sepsis was controlled (defervescence of fever and return of WBC to normal) in an additional nine patients, allowing elective pancreatic surgery for control of pancreatic duct fistula. Eight patients failed to show clinical improvement after drainage and required necrosectomy. No patient experienced catheter-related complications. Mortality was 12% (all four deaths occurred after necrosectomy because of multiorgan failure).
CONCLUSION:
Percutaneous catheter drainage is a safe and effective technique for treating infected acute necrotizing pancreatitis. Overall, sepsis was controlled in 74% of patients, permitting elective surgery for treatment of pancreatic fistula, and 47% of patients were cured with no surgery required. No catheter-related complications occurred.
AuthorsP C Freeny, E Hauptmann, S J Althaus, L W Traverso, M Sinanan
JournalAJR. American journal of roentgenology (AJR Am J Roentgenol) Vol. 170 Issue 4 Pg. 969-75 (Apr 1998) ISSN: 0361-803X [Print] United States
PMID9530046 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Topics
  • Adult
  • Aged
  • Bacterial Infections (complications, diagnostic imaging, therapy)
  • Catheterization (methods)
  • Drainage (methods)
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pancreatitis, Acute Necrotizing (diagnostic imaging, microbiology, therapy)
  • Radiography, Interventional
  • Tomography, X-Ray Computed

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: