Abstract | BACKGROUND: METHOD: In a naturalistic setting, by reviewing medical records, we assessed response to olanzapine and factors associated with response to olanzapine in 150 consecutive patients newly treated with the drug at a nonprofit academic psychiatric hospital. RESULTS: Patients displaying a moderate-to-marked response to olanzapine were more likely to be younger; be female; receive a diagnosis of bipolar disorder; and have a shorter duration of illness, shorter length of stay prior to olanzapine, and longer duration of trial. CONCLUSION:
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Authors | C A Zarate Jr, R Narendran, M Tohen, J J Greaney, A Berman, S Pike, A Madrid |
Journal | The Journal of clinical psychiatry
(J Clin Psychiatry)
Vol. 59
Issue 1
Pg. 24-8
(Jan 1998)
ISSN: 0160-6689 [Print] United States |
PMID | 9491062
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antipsychotic Agents
- Benzodiazepines
- Pirenzepine
- Haloperidol
- Olanzapine
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Topics |
- Adolescent
- Adult
- Affective Disorders, Psychotic
(drug therapy)
- Age Factors
- Antipsychotic Agents
(therapeutic use)
- Benzodiazepines
- Bipolar Disorder
(drug therapy)
- Controlled Clinical Trials as Topic
- Drug Administration Schedule
- Drug Therapy, Combination
- Female
- Haloperidol
(therapeutic use)
- Humans
- Male
- Middle Aged
- Olanzapine
- Pirenzepine
(analogs & derivatives, therapeutic use)
- Retrospective Studies
- Sex Factors
- Treatment Outcome
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