Bath-PUVA therapy in three patients with scleredema adultorum.

Abstract

BACKGROUND:

Scleredema adultorum (SA) is a rare connective tissue disorder for which no treatment has proven to be effective.

OBJECTIVE:

Our purpose was to determine the effect of bath-PUVA therapy on SA.

METHODS:

Three patients were treated. Clinical evaluation of skin induration and thickness as well as ultrasonography were performed at baseline and after treatment.

RESULTS:

All three patients showed substantial clinical improvement with bath-PUVA therapy (median of 59 treatments and a cumulative UVA dose of 245.7 J/cm2). Ultrasonography showed significant reduction in both skin thickness and density.

CONCLUSION:

Bath-PUVA therapy appears to be effective in the treatment of SA.

• Authors: C M Hager, H A Sobhi, N Hunzelmann, C Wickenhauser, R Scharenberg, T Krieg, K Scharffetter-Kochanek
• Journal: Journal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 38 Issue 2 Pt 1 Pg. 240-2 (Feb 1998) ISSN: 0190-9622 [Print] United States
• PMID: 9486680 (Publication Type: Case Reports, Journal Article)

Topics

• Humans
• Male
• Middle Aged
• PUVA Therapy
• Radiotherapy Dosage
• Scleredema Adultorum (drug therapy, pathology)