Abstract | OBJECTIVE: METHODS: Medical records, histological slides, and radiological films were reviewed for a patient with metastatic PSTT diagnosed in 1991. Using Medline and cross-references, pertinent articles were reviewed. RESULTS: A 31-year-old patient with PSTT metastatic to the lungs and vagina is presently alive, without evidence of recurrent cancer, more than 6 years after treatment with EMA/CO chemotherapy and surgery. The total response rate for seven patients with metastatic PSTT treated with EMA/CO chemotherapy was 71% with a complete response rate of 28%. CONCLUSIONS: Metastatic PSTT is potentially curable. EMA/CO chemotherapy appears superior to older multiagent regimens used in treating PSTT.
|
Authors | E Swisher, C W Drescher |
Journal | Gynecologic oncology
(Gynecol Oncol)
Vol. 68
Issue 1
Pg. 62-5
(Jan 1998)
ISSN: 0090-8258 [Print] United States |
PMID | 9454662
(Publication Type: Case Reports, Journal Article)
|
Copyright | Copyright 1998 Academic Press. |
Chemical References |
- Dactinomycin
- Vincristine
- Etoposide
- Cyclophosphamide
- Methotrexate
|
Topics |
- Adult
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Cyclophosphamide
(administration & dosage)
- Dactinomycin
(administration & dosage)
- Etoposide
(administration & dosage)
- Female
- Humans
- Lung Neoplasms
(diagnostic imaging, secondary)
- Methotrexate
(administration & dosage)
- Pregnancy
- Radiography
- Remission Induction
- Trophoblastic Tumor, Placental Site
(drug therapy, pathology)
- Uterine Neoplasms
(drug therapy, pathology)
- Vaginal Neoplasms
(secondary)
- Vincristine
(administration & dosage)
|