Failure analysis in irradiated stage I testicular seminoma. Results of long-term follow-up (1968-1993).

Abstract

A retrospective analysis of 81 stage I seminoma patients irradiated at the Northern Israel Oncology Center between 1968 and 1993 was undertaken. During this period, 5 (6%) patients relapsed, all outside the initial treatment volume, with a median time of 6.6 (range 1-12) months to relapse. Three patients were salvaged with cisplatin-based chemotherapy. The policy of adjuvant radiotherapy resulted in a high probability of cure and decreased relapse rate. Early relapse is a rare event in properly irradiated stage I seminoma which is highly curable with a cisplatin-containing regimen. Recurrences tend to occur outside the treated radiation volume.

• Authors: M E Stein, K Drumea, B Moshkowitz, O Nativ, A Kuten
• Journal: Urologia internationalis (Urol Int) Vol. 59 Issue 3 Pg. 200-2 ( 1997) ISSN: 0042-1138 [Print] Switzerland
• PMID: 9428443 (Publication Type: Journal Article)

Chemical References

• Antineoplastic Agents
• Cisplatin

Topics

• Antineoplastic Agents (therapeutic use)
• Cisplatin (therapeutic use)
• Follow-Up Studies
• Humans
• Male
• Neoplasm Recurrence, Local
• Neoplasm Staging
• Radiotherapy, Adjuvant (methods)
• Retrospective Studies
• Salvage Therapy
• Seminoma (drug therapy, radiotherapy)
• Testicular Neoplasms (drug therapy, radiotherapy)
• Treatment Failure
• Treatment Outcome