Abstract |
Over a period of years, insulin-dependent diabetes and respiratory insufficiency developed in a 35-year-old patient with end-stage cystic fibrosis. After waiting more than 4 years while receiving maintenance treatment with continuous liquid O2 and nasal ventilation, the patient underwent double-lung and pancreatic islet cell transplantation. Subsequently, the patient has enjoyed a normal life with full employment and much better control of his diabetes. Pancreatic islet cell transplantation is a simple and innocuous technique easily added to the end of lung transplantation. These new pancreatic cells, although locally injected, are still secreting more than 2 years later as assessed by repeated C-peptide measurements.
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Authors | J M Tschopp, M H Brutsche, J G Frey, A Spiliopoulos, L Nicod, T Rochat, P Morel |
Journal | Chest
(Chest)
Vol. 112
Issue 6
Pg. 1685-7
(Dec 1997)
ISSN: 0012-3692 [Print] United States |
PMID | 9404774
(Publication Type: Case Reports, Journal Article, Review)
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Topics |
- Acute Disease
- Adult
- Combined Modality Therapy
- Cystic Fibrosis
(surgery)
- Diabetes Mellitus, Type 1
(surgery)
- Follow-Up Studies
- Humans
- Islets of Langerhans Transplantation
- Lung Transplantation
- Male
- Remission Induction
- Respiratory Insufficiency
(surgery)
- Time Factors
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