Radiochemical synovectomy.

Abstract

Radiochemical synovectomies have been used for nearly fifty years for the treatment of persistent monoarticular synovitis refractory to antiinflammatory drugs, disease modifying drugs, and intraarticular corticosteroids. It is a therapeutic alternative to surgical synovectomy. There are controversies concerning safety, choice of appropriate agent, and logistics of administration. These concerns are discussed in addition to reviewing some of the more recent trials examining the efficacy of radiochemical synovectomy. It is clear that in properly selected patients this procedure is safe and beneficial.

• Authors: D Sholter, P Davis
• Journal: Scandinavian journal of rheumatology (Scand J Rheumatol) Vol. 26 Issue 5 Pg. 337-41 ( 1997) ISSN: 0300-9742 [Print] England
• PMID: 9385342 (Publication Type: Editorial, Review)

Chemical References

• Anti-Inflammatory Agents
• Steroids
• Yttrium Radioisotopes

Topics

• Anti-Inflammatory Agents (therapeutic use)
• Arthritis, Rheumatoid (radiotherapy)
• Humans
• Knee Joint (radiation effects)
• Steroids
• Synovial Membrane (radiation effects)
• Synovitis (radiotherapy)
• Yttrium Radioisotopes (adverse effects, therapeutic use)