The treatment of steroid-induced bone loss in transplantation.

Abstract

Osteopenia after transplantation is a significant cause of morbidity. Despite the lack of randomized, placebo-controlled trials in renal transplantation, there is literature supporting both the prevention and treatment of existing corticosteroid-induced osteoporosis with antiresorptive agents, such as calcitonin and bisphosphonates. The newer pharmacologic agents, nasal spray calcitonin and alendronate, have shown promising results in postmenopausal osteoporosis, and their ease of administration and low incidence of side effects make them ideal for renal transplant patients.

• Authors: S M Moe
• Journal: Current opinion in nephrology and hypertension (Curr Opin Nephrol Hypertens) Vol. 6 Issue 6 Pg. 544-9 (Nov 1997) ISSN: 1062-4821 [Print] England
• PMID: 9375268 (Publication Type: Journal Article, Review)

Chemical References

• Steroids

Topics

• Bone Diseases, Metabolic (etiology, therapy)
• Female
• Humans
• Kidney Transplantation
• Steroids (adverse effects)