HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Anosognosia and confabulation during the Wada test.

Abstract
Feinberg et al. proposed that right-hemisphere-damaged stroke patients with anosognosia for hemiplegia (AHP) confabulate seeing stimuli on the left side but those without AHP admit to having inadequate visual information. This study examines the relationship between AHP and confabulation using selective anesthesia of the cerebral hemispheres. Seventeen patients with intractable epilepsy were tested during intracarotid methohexital infusion. For half of the trials, subjects were stimulated on their paretic hand with a material (sandpaper, metal, or cloth), and for the remaining trials they were not stimulated. The subjects were trained to use a pointing response to indicate if they been stimulated and the type of material they had felt. Admission of uncertainty was defined as pointing to a question mark. Confabulation was defined as any material response to a no-touch trial. During anesthesia of either hemisphere, subjects with and without AHP confabulated responses. The AHP and non-AHP groups did not differ in admission of uncertainty. Our results support the postulate that confabulation and AHP are independent disorders, and therefore confabulation cannot fully account for AHP.
AuthorsL H Lu, A M Barrett, R L Schwartz, J E Cibula, R L Gilmore, B M Uthman, K M Heilman
JournalNeurology (Neurology) Vol. 49 Issue 5 Pg. 1316-22 (Nov 1997) ISSN: 0028-3878 [Print] United States
PMID9371915 (Publication Type: Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Anesthetics, Intravenous
  • Methohexital
Topics
  • Adolescent
  • Adult
  • Aged
  • Agnosia (physiopathology, psychology)
  • Anesthetics, Intravenous
  • Carotid Arteries
  • Dominance, Cerebral (physiology)
  • Epilepsy (diagnosis, physiopathology, psychology)
  • Fantasy
  • Female
  • Humans
  • Injections, Intra-Arterial
  • Male
  • Memory Disorders (physiopathology, psychology)
  • Methohexital
  • Middle Aged
  • Neuropsychological Tests
  • Reality Testing
  • Verbal Behavior (physiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: