The selective recognition of antibody IgY for digestive system cancers.

Abstract

Biological methods for cancer therapies are very important. A small and efficient target carrier is the key component for anti-cancer drugs. In our laboratory, the antibody IgY was extracted from egg yolk of a SPF hen. The SPF hen was immunized with an antigene of P110 protein which was purified from human stomach cancer MGC-803 cells. Results indicated that the antibody IgY can specifically recognize gastrointestinal system cancers. It may become an important carrier for antitumorigenic drugs.

• Authors: J Yang, Z Jin, Q Yu, T Yang, H Wang, L Liu
• Journal: Chinese journal of biotechnology (Chin J Biotechnol) Vol. 13 Issue 2 Pg. 85-90 ( 1997) ISSN: 1042-749X [Print] United States
• PMID: 9343706 (Publication Type: Journal Article)

Chemical References

• Antibodies, Neoplasm
• Antigens, Neoplasm
• IgY
• Immunoglobulins

Topics

• Adenocarcinoma (immunology)
• Animals
• Antibodies, Neoplasm (immunology)
• Antigens, Neoplasm (analysis, immunology)
• Blotting, Western
• Chickens
• Electrophoresis, Polyacrylamide Gel
• Humans
• Immunoglobulins (immunology, isolation & purification)
• Rabbits
• Stomach Neoplasms (immunology)
• Tumor Cells, Cultured