Sustained response to interferon in a patient with common variable immunodeficiency and hepatitis C.

Abstract

Hepatitis C infection progresses faster in patients with hypogammaglobulinemia, often leading to death from liver failure within 10 yr of exposure. Response to interferon treatment has been poor in these patients. We report the case of a patient with common variable immunodeficiency and hepatitis C in whom a sustained biochemical and viral remission was obtained after treatment with interferon.

• Authors: F Castro, M Santaella, E A Torres, J R Rodriguez-Medina, C González-Keelan
• Journal: The American journal of gastroenterology (Am J Gastroenterol) Vol. 92 Issue 9 Pg. 1557-8 (Sep 1997) ISSN: 0002-9270 [Print] United States
• PMID: 9317087 (Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Antiviral Agents
• Immunoglobulins, Intravenous
• Interferon alpha-2
• Interferon-alpha
• RNA, Viral
• Recombinant Proteins

Topics

• Adult
• Antiviral Agents (therapeutic use)
• Cause of Death
• Common Variable Immunodeficiency (complications, therapy)
• Disease Progression
• Drug Contamination
• Female
• Hepacivirus (genetics, isolation & purification)
• Hepatitis C (complications, therapy)
• Hepatitis, Chronic (complications, therapy)
• Humans
• Immunoglobulins, Intravenous (therapeutic use)
• Interferon alpha-2
• Interferon-alpha (therapeutic use)
• Liver Failure (etiology)
• Prognosis
• RNA, Viral (analysis, genetics)
• Recombinant Proteins