[Effect of low-intensity radiation on the course of experimental tick-borne encephalitis].

Abstract

Effects of low-intensive laser exposure in the 630 to 890 nm waveband on the course of experimental tick-borne encephalitis were studied in vitro and in vivo. Virus-static effect of the exposure was revealed: titers of the exposed virus dropped, infective activity decreased, and interferon production was inhibited. The exposure had no apparent effect on the virus which penetrated into the cells. In addition to its manifest prophylactic effect, low-intensive laser exposure is capable of activating the infectious process during the acute period of tick-borne encephalitis by causing more frequent and sooner death of animals. Effects of interferon inducers during the acute period of viral infections are discussed.

• Authors: G N Leonova, O S Maĭstrovskaia, N V Krylova
• Journal: Voprosy virusologii (Vopr Virusol) 1997 May-Jun Vol. 42 Issue 3 Pg. 129-33 ISSN: 0507-4088 [Print] Russia (Federation)
• Vernacular Title: Vliianie nizkointensivnykh izlucheniĭ na techenie éksperimental'nogo kleshchevogo éntsefalita.
• PMID: 9297344 (Publication Type: English Abstract, Journal Article)

Chemical References

• Interferon Inducers
• Interferons

Topics

• Animals
• Encephalitis Viruses, Tick-Borne (pathogenicity, radiation effects)
• Encephalitis, Tick-Borne (metabolism, physiopathology)
• Humans
• In Vitro Techniques
• Interferon Inducers (pharmacology)
• Interferons (biosynthesis)
• Lasers
• Mice