Lymphangiomas in children: percutaneous sclerotherapy with an alcoholic solution of zein.

Abstract

PURPOSE:

To determine the efficacy of percutaneous sclerotherapy with an alcoholic solution of zein in lymphangiomas in pediatric patients.

MATERIALS AND METHODS:

Fourteen patients with macrocystic and mixed lymphangiomas were treated with use of Ethibloc as a sclerosing agent. The procedure was performed with ultrasonographic and/or fluoroscopic guidance. Follow-up clinical and sequential computed tomographic examinations were performed to evaluate regression of the lesion.

RESULTS:

Regression was excellent in nine (64%) of the 14 lesions: Regression was complete in four lymphangiomas and was to less than 5% of the initial volume in five. Satisfactory results were obtained in the remaining five (36%) of 14 lesions. The most frequent complication was leakage of Ethibloc without important sequelae in 10 of the 14 lymphangiomas.

CONCLUSION:

Percutaneous sclerotherapy with Ethibloc was a safe and effective procedure in the treatment of macrocystic and mixed lymphangiomas.

• Authors: J Dubois, L Garel, A Abela, L Laberge, S Yazbeck
• Journal: Radiology (Radiology) Vol. 204 Issue 3 Pg. 651-4 (Sep 1997) ISSN: 0033-8419 [Print] United States
• PMID: 9280239 (Publication Type: Journal Article)

Chemical References

• Drug Combinations
• Fatty Acids
• Propylene Glycols
• Sclerosing Solutions
• Diatrizoate
• Zein
• alcoholic prolamine solution

Topics

• Adolescent
• Axilla
• Child
• Child, Preschool
• Diatrizoate (adverse effects, therapeutic use)
• Drug Combinations
• Fatty Acids (adverse effects, therapeutic use)
• Female
• Follow-Up Studies
• Head and Neck Neoplasms (therapy)
• Humans
• Infant
• Infant, Newborn
• Lymphangioma (therapy)
• Male
• Propylene Glycols (adverse effects, therapeutic use)
• Prospective Studies
• Radiography, Interventional
• Sclerosing Solutions (adverse effects, therapeutic use)
• Sclerotherapy
• Ultrasonography, Interventional
• Zein (adverse effects, therapeutic use)