HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

The role of O1-antigen in the adhesion to uroepithelial cells of Klebsiella pneumoniae grown in urine.

Abstract
We obtained mutants devoid of the O1-antigen, the capsular polysaccharide (K antigen) or both from Klebsiella pneumoniae clinical isolates (urinary infection). These mutants were grown in urine, and their ability to fimbriate and to adhere were studied. Mutants lacking the O1-antigen, independently of the other surface molecules (capsule and fimbriae), showed a great decrease in adhesion to these cells.
AuthorsS Merino, X Rubires, A Aguilar, J M Tomás
JournalMicrobial pathogenesis (Microb Pathog) Vol. 23 Issue 1 Pg. 49-53 (Jul 1997) ISSN: 0882-4010 [Print] England
PMID9250780 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Antigens, Bacterial
  • O Antigens
Topics
  • Antigens, Bacterial (immunology)
  • Bacterial Adhesion (immunology)
  • Cells, Cultured
  • Epithelium (microbiology)
  • Female
  • Humans
  • Klebsiella pneumoniae (cytology, immunology)
  • O Antigens (immunology)
  • Urine (microbiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: