Ultrastructure of a cardiac rhabdomyoma.

Abstract

Electron microscopic study of a cardiac rhabdomyoma removed at open heart operation revealed large rounded or polygonal cells that contained large amounts of monoparticulate glycogen. Myofibrils in these cells were few and located either subjacent to the plasma membranes or radiating from central areas. Leptofibrils and masses of anomalous Z band material were abundant. Shallow tubular sarcolemmal invaginations and elements of free and junctional sarcoplasmic reticulum were associated with the myofibrils. Desmosomes and nexuses were evident in intercellular junctions, which were extensive and randomly distributed throughout the cell surfaces. It is concluded that cardiac rhabdomyomas probably are hamartomas.

• Authors: J J Fenoglio Jr, D J Diana, T E Bowen, H A McAllister Jr, V J Ferrans
• Journal: Human pathology (Hum Pathol) Vol. 8 Issue 6 Pg. 700-6 (Nov 1977) ISSN: 0046-8177 [Print] United States
• PMID: 924433 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glycogen

Topics

• Cell Membrane (ultrastructure)
• Cell Nucleus (ultrastructure)
• Glycogen (analysis)
• Heart Neoplasms (ultrastructure)
• Humans
• Infant
• Intercellular Junctions (ultrastructure)
• Myofibrils (ultrastructure)
• Organoids (ultrastructure)
• Rhabdomyoma (ultrastructure)
• Sarcoplasmic Reticulum (ultrastructure)