[Dapsone in granulomatous rosacea].

Abstract

We report on two patients with granulomatous rosacea and another patient with granulomatous perioral dermatitis who responded well to dapsone. Dapsone has a pharmacological double function as both an antibiotic and an antiphlogistic drug. Before the introduction of isotretinoin, dapsone had its place in the treatment of severe acne. To date, its use in granulomatous rosacea has not been described. When hematologic parameters are monitored, dapsone is considered a safe and cost-effective drug, especially in countries where isotretinoin is not readily available. However, the definite value of dapsone in granulomatous rosacea should be established by a controlled study.

• Authors: M H Krause, R Torricelli, T Kündig, R M Trüeb, J Hafner
• Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete (Hautarzt) Vol. 48 Issue 4 Pg. 246-8 (Apr 1997) ISSN: 0017-8470 [Print] Germany
• Vernacular Title: Dapson bei granulomatöser Rosazea.
• PMID: 9206712 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Anti-Infective Agents
• Dapsone

Topics

• Adult
• Anti-Infective Agents (administration & dosage, adverse effects)
• Biopsy
• Dapsone (administration & dosage, adverse effects)
• Facial Dermatoses (drug therapy, pathology)
• Female
• Humans
• Male
• Middle Aged
• Rosacea (drug therapy, pathology)
• Skin (pathology)