Inositol treatment of autism.

Abstract

Recent studies suggest that serotonin reuptake inhibitors are helpful in at least some symptoms of autism. Inositol is a precursor of the second messenger for some serotonin receptors, and has been reported effective in depression, panic disorder and obsessive-compulsive disorder. However a controlled double-blind crossover trial of inositol 200 mg/kg per day showed no benefit on 9 children with autism. Since biochemical studies could evaluate inositol in children already receiving serotonin reuptake inhibitors.

• Authors: J Levine, A Aviram, A Holan, A Ring, Y Barak, R H Belmaker
• Journal: Journal of neural transmission (Vienna, Austria : 1996) (J Neural Transm (Vienna)) Vol. 104 Issue 2-3 Pg. 307-10 ( 1997) ISSN: 0300-9564 [Print] Austria
• PMID: 9203092 (Publication Type: Clinical Trial, Journal Article)

Chemical References

• Inositol

Topics

• Autistic Disorder (drug therapy, psychology)
• Child
• Child, Preschool
• Cross-Over Studies
• Double-Blind Method
• Female
• Humans
• Inositol (therapeutic use)
• Male
• Psychiatric Status Rating Scales