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Tissue plasminogen activator in a vertebral artery dissection.

AbstractBACKGROUND:
Spontaneous dissection of the vertebral artery is uncommon.
METHOD:
Case study.
RESULTS:
We report a 49-year-old woman who presented with the rapidly progressing basilar artery syndrome who was given an intravenous dose of tissue plasminogen activator seven hours after the onset of first symptoms. Thirty minutes after the injection, a dramatic recovery of the patient's consciousness and neurological signs was noted.
CONCLUSION:
To our knowledge, this is the first reported case of intravenous tissue plasminogen activator use in acute vertebral artery dissection.
AuthorsA P Gasecki, C Graffagnino, V Hachinski
JournalThe Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques (Can J Neurol Sci) Vol. 24 Issue 2 Pg. 151-4 (May 1997) ISSN: 0317-1671 [Print] England
PMID9164694 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Tissue Plasminogen Activator
Topics
  • Arterial Occlusive Diseases (pathology)
  • Cerebral Angiography
  • Female
  • Humans
  • Injections, Intravenous
  • Intracranial Embolism and Thrombosis (drug therapy, pathology)
  • Magnetic Resonance Imaging
  • Middle Aged
  • Tissue Plasminogen Activator (administration & dosage, therapeutic use)
  • Vertebral Artery (pathology)

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