Abstract |
The clinical profile of 33 children (19 boys, 14 girls) with multiple congenital contractures has been studied. The majority (54%) belong to arthrogryposis multiplex congenita with a static clinical course. Children were classified into three groups: group I (limb involvement only; n = 21) having arthrogryposis multiplex congenita (n = 18), distal arthrogryposis syndrome (n = 2) and Streeter syndrome (n = 1); group II (limb involvement with other malformation or anomalies; n = 7) having congenital contractural arachnodactyly (n = 3), Larsen syndrome (n = 1), multiple pterygium syndrome (n = 1), craniocarpotarsal dystrophy (n = 1), and Schwartz Jampel syndrome (n = 1); and group III (limb involvement with central nervous system dysfunction or mental retardation; n = 5) having myotonia dystrophica (n = 2), congenital muscular dystrophy (n = 1), foetal alcohol syndrome (n = 1) and Pena-Shokeir syndrome (n = 1). Three children died, one each of arthrogryposis multiplex congenita, congenital contractural arachnodactyly and myotonia dystrophica. The majority had a good prognosis with independent function and mobility.
|
Authors | V Wong |
Journal | Brain & development
(Brain Dev)
Vol. 19
Issue 3
Pg. 187-96
(Apr 1997)
ISSN: 0387-7604 [Print] Netherlands |
PMID | 9134190
(Publication Type: Journal Article)
|
Topics |
- Abnormalities, Multiple
(diagnosis)
- Adolescent
- Adult
- Amniotic Band Syndrome
(complications, diagnosis)
- Arthrogryposis
(classification, complications, mortality)
- Asian People
- Child
- Child, Preschool
- Female
- Fetal Alcohol Spectrum Disorders
(complications, diagnosis)
- Humans
- Infant
- Infant, Newborn
- Intellectual Disability
(complications, diagnosis)
- Male
- Muscular Dystrophies
(complications, diagnosis)
- Myotonia
(complications, diagnosis)
- Osteochondrodysplasias
(complications, diagnosis)
- Prognosis
|