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Coexistence of a graft with the preserved native liver in auxiliary partial orthotopic liver transplantation from a living donor for ornithine transcarbamylase deficiency.

AbstractBACKGROUND:
Auxiliary partial orthotopic liver transplantation (APOLT) has recently been performed in patients with noncirrhotic metabolic liver diseases. However, long-term outcomes for the preserved native liver and the transplanted liver graft have not been clearly established yet.
METHODS:
The recipient was a 36-month-old girl with ornithine transcarbamylase deficiency. She underwent APOLT, using her father's left lateral segment.
RESULTS:
Liver function was normalized soon after APOLT and the patient was able to ingest a normal diet without medication. Coexistence of the well-functioning native liver and graft was demonstrated in a computed tomography scan, Doppler ultrasonography, scintigraphy, and histological examination, during a relatively long-term follow-up period.
CONCLUSIONS:
APOLT seems to be most useful for the treatment of noncirrhotic metabolic liver diseases.
AuthorsS Uemoto, S Yabe, Y Inomata, H Nishizawa, K Asonuma, H Egawa, T Kiuchi, H Okajima, Y Yamaoka, H Yamabe, A Inui, T Fujisawa, K Tanaka
JournalTransplantation (Transplantation) Vol. 63 Issue 7 Pg. 1026-8 (Apr 15 1997) ISSN: 0041-1337 [Print] United States
PMID9112359 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
Topics
  • Biopsy
  • Child, Preschool
  • Female
  • Humans
  • Liver (diagnostic imaging, pathology, physiology)
  • Liver Transplantation (diagnostic imaging, methods, pathology, physiology)
  • Ornithine Carbamoyltransferase Deficiency Disease
  • Radiography

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