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[High-dose methylprednisolone pulse therapy for respiratory failure after open heart surgery].

Abstract
After open-heart surgery, we sometime experience a patient whose respiratory function worsens extremely, though a heart function is improved. We experienced four such cases and treated with high-dose methylprednisolone. Then, we recognized that the respiratory function was improved at all cases. However, one case deteriorated again regarding the respiratory function, as a start of the treatment was delayed. There is a possibility that host resistance to infection is decreased by administration of corticosteroids. Therefore, we hesitate to treat with corticosteroids. Concerning respiratory failure after open heart surgery, however, we think that a respiratory function of a patient is improved if high-dose methylprednisolone pulse therapy is started in early stage.
AuthorsH Kurata, I Yamazaki, M Ishii, Y Yano, M Kase, I Tomiyama
JournalKyobu geka. The Japanese journal of thoracic surgery (Kyobu Geka) Vol. 50 Issue 4 Pg. 292-7 (Apr 1997) ISSN: 0021-5252 [Print] Japan
PMID9095589 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Methylprednisolone
Topics
  • Aged
  • Angina Pectoris (surgery)
  • Coronary Artery Bypass
  • Drug Administration Schedule
  • Humans
  • Male
  • Methylprednisolone (administration & dosage)
  • Middle Aged
  • Postoperative Complications (drug therapy)
  • Respiratory Insufficiency (drug therapy)

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