Efficacy of doramectin against intestinal nematodes and sarcoptic manage mites in naturally infected swine.

Abstract

Endectocidal efficacy of doramectin administered intramuscularly at a dosage of 300 micrograms/kg was evaluated in 464 pigs naturally infected with intestinal nematodes or mange mites on 14 commercial farms in Japan. By doramectin treatment, fecal egg counts were reduced > 99% for Ascaris suum, Strongyloides ransomi, Oesophagostomum dentatum, and Trichuris suis; worm counts of T. suis and mite counts of Sarcoptes scabiei reduced 90.1% on Day 21 and 99.5% on Day 28 following treatment, respectively.

• Authors: H Saeki, T Fujii, S Fukumoto, K Kagota, A Taneichi, S Takeda, M Tsukaguchi
• Journal: The Journal of veterinary medical science (J Vet Med Sci) Vol. 59 Issue 2 Pg. 129-32 (Feb 1997) ISSN: 0916-7250 [Print] Japan
• PMID: 9070986 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)

Chemical References

• Anthelmintics
• Ivermectin
• doramectin

Topics

• Animals
• Anthelmintics (administration & dosage, therapeutic use)
• Ascariasis (drug therapy, veterinary)
• Ascaris suum (isolation & purification)
• Feces (parasitology)
• Female
• Injections, Intravenous (veterinary)
• Intestinal Diseases, Parasitic (drug therapy, veterinary)
• Ivermectin (administration & dosage, analogs & derivatives, therapeutic use)
• Nematode Infections (drug therapy, veterinary)
• Oesophagostomiasis (drug therapy, veterinary)
• Oesophagostomum (isolation & purification)
• Parasite Egg Count (veterinary)
• Scabies (drug therapy, veterinary)
• Skin (parasitology)
• Strongyloides (isolation & purification)
• Strongyloidiasis (drug therapy, veterinary)
• Swine
• Swine Diseases (drug therapy)
• Time Factors
• Trichuriasis (drug therapy, veterinary)
• Trichuris (isolation & purification)