[LP-X in the first month of life (author's transl)].

Abstract

An abnormal lipoprotein can be detected in the sera of patients suffering from intra- and extrahepatic cholestasis. The specificity of LP-X detection for the diagnosis of cholestasis in adult persons was proved by extensive investigations. The aim of this study was to examine the specificity of LP-X with regard to cholestasis in the postnatal phase of premature and newborn infants. 1056 sera of 270 newborns were tested and in 75% of these cases LP-X was found to be positive. Three hypothetical explanations are given concerning the appearance of LP-X in the sera of premature and newborn infants. The semi-quantitative determination of LP-X also represents a possibility for differential diagnosis of obstructive jaundice in the neonatal period.

• Authors: D Lachmann, G Eder
• Journal: Padiatrie und Padologie (Padiatr Padol) Vol. 12 Issue 4 Pg. 334-8 ( 1977) ISSN: 0030-9338 [Print] Austria
• Vernacular Title: Die Bedeutung von LP-X in den ersten Lebensmonaten.
• PMID: 904943 (Publication Type: English Abstract, Journal Article)

Chemical References

• Lipoproteins
• Alkaline Phosphatase
• Bilirubin

Topics

• Adult
• Age Factors
• Alkaline Phosphatase (blood)
• Bilirubin (blood)
• Birth Weight
• Cholestasis (blood, enzymology)
• Humans
• Infant, Newborn
• Infant, Newborn, Diseases (blood)
• Infant, Premature
• Infant, Premature, Diseases (blood)
• Lipoproteins (blood)
• Time Factors