Abstract | OBJECTIVE: PATIENTS AND METHODS: The study comprised 31 patients (mean age 64.4 years, range 55-89) facing a prolonged wait for prostatectomy: in group 1, 14 patients presented in acute urinary retention and had an indwelling urethral catheter; in group 2, six patients had indwelling catheters but removal was deemed necessary to control urinary tract infection: in group 3, 11 patients had troublesome symptoms from BPH but no retention. Some of the patients were also hypertensive. After receiving I mg of prazosin twice daily, the catheters were removed at various intervals and the effect on symptom scores and residual urine volume determined after one week and 2 months. RESULTS: CONCLUSION: The use of this alpha blocker for BPH in the absence of facilities to measure urinary flow rate, intravesical pressure and serum prostate specific antigen can be justified for short periods. However, a large default rate among these patients raises additional questions about long-term safety and underlines the importance of selecting patients carefully.
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Authors | B C Ogbonna, B N Okeahialam, V M Ramyil |
Journal | British journal of urology
(Br J Urol)
Vol. 79
Issue 1
Pg. 32-5
(Jan 1997)
ISSN: 0007-1331 [Print] England |
PMID | 9043492
(Publication Type: Journal Article)
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Chemical References |
- Adrenergic alpha-Antagonists
- Prazosin
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Topics |
- Adrenergic alpha-Antagonists
(adverse effects, therapeutic use)
- Aged
- Aged, 80 and over
- Heart Diseases
(chemically induced)
- Humans
- Hypertension
(chemically induced)
- Male
- Middle Aged
- Nigeria
- Prazosin
(adverse effects, therapeutic use)
- Prostatectomy
- Prostatic Hyperplasia
(complications, drug therapy, physiopathology)
- Urinary Catheterization
- Urinary Retention
(etiology)
- Urinary Tract Infections
(etiology)
- Urination
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