Abstract | OBJECTIVE: METHODS: RESULTS: Patients treated with glucose- insulin- potassium solution had higher cardiac indices (2.8 +/- 0.1 vs 2.0 +/- 1 L/min per square meter; p < 0.001), lower inotrope scores (0.06 +/- 0.01 vs 0.46 +/- 0.19; p = 0.041), and less weight gain (6.4 +/- 9 vs 11.6 +/- 1.1 pounds; p < 0.001) and had shorter times of ventilator support (8.3 +/- 0.6 vs 14.2 +/- 0.2 hours; p = 0.003). They had a significantly lower incidence of atrial fibrillation (13.3% vs 53.3%; p = 0.020) and had shorter stays in the intensive care unit (14.8 +/- 1.3 vs 31.6 +/- 5.2 hours; p = 0.002) and in the hospital (6.0 +/- 0.4 vs 8.0 +/- 0.7 days; p = 0.010). CONCLUSIONS:
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Authors | H L Lazar, G Philippides, C Fitzgerald, D Lancaster, R J Shemin, C Apstein |
Journal | The Journal of thoracic and cardiovascular surgery
(J Thorac Cardiovasc Surg)
Vol. 113
Issue 2
Pg. 354-60; discussion 360-2
(Feb 1997)
ISSN: 0022-5223 [Print] United States |
PMID | 9040630
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Cardioplegic Solutions
- Insulin
- glucose-insulin-potassium cardioplegic solution
- Glucose
- Potassium
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Angina, Unstable
(drug therapy)
- Atrial Fibrillation
(etiology)
- Cardioplegic Solutions
(therapeutic use)
- Coronary Artery Bypass
- Emergencies
- Female
- Glucose
(therapeutic use)
- Humans
- Insulin
(therapeutic use)
- Male
- Middle Aged
- Postoperative Complications
- Potassium
(therapeutic use)
- Prospective Studies
- Treatment Outcome
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