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Guillain-Barré syndrome and ethylene diamine tetraacetic acid-dependent pseudothrombocytopenia associated with mumps.

Abstract
A 35-year-old man with Guillain-Barré syndrome and ethylene diamine tetraacetic acid (EDTA)-dependent pseudothrombocytopenia associated with serologically-confirmed mumps is presented. A polyneuropathy developed 18 days after the onset of mumps, that improved with plasmapheresis. A decreased platelet count was observed 25 days after the onset of mumps attributed to platelet agglutination in blood anticoagulated with EDTA, and the agglutination was prevented by other anticoagulants. Guillain-Barré syndrome associated with mumps is rare and EDTA-dependent pseudothrombocytopenia following mumps has never been documented. This represents the first report of Guillain-Barré syndrome and EDTA-dependent pseudothrombocytopenia following mumps. Furthermore, our findings suggest activation of the humoral immune response as a potential pathogenesis.
AuthorsA Sawazaki, N Nakamura, H Jyokaji, S Minami, S Nakamura, T Matsuda
JournalInternal medicine (Tokyo, Japan) (Intern Med) Vol. 35 Issue 12 Pg. 996-9 (Dec 1996) ISSN: 0918-2918 [Print] Japan
PMID9031003 (Publication Type: Case Reports, Journal Article, Review)
Chemical References
  • Edetic Acid
Topics
  • Adult
  • Edetic Acid
  • Humans
  • Male
  • Mumps (complications)
  • Polyradiculoneuropathy (etiology)
  • Thrombocytopenia (etiology)

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