Abstract |
Doxycycline provided satisfactory prophylaxis against experimental infection with a highly pathogenic strain of Babesia canis. Rectal temperature, parasitaemia, packed cell volume and serology were monitored for evaluation of the prophylactic effect. Although a daily dose of 5 mg kg-1 of doxycycline did not completely prevent clinical disease, symptoms remained moderate and a full recovery was obtained within 1 week. At a dose of 20 mg kg-1 day-1 no clinical symptoms were observed, but asymptomatic infection could not be ruled out.
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Authors | F Vercammen, R De Deken, L Maes |
Journal | Veterinary parasitology
(Vet Parasitol)
Vol. 66
Issue 3-4
Pg. 251-5
(Nov 15 1996)
ISSN: 0304-4017 [Print] Netherlands |
PMID | 9017887
(Publication Type: Journal Article)
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Chemical References |
- Antiprotozoal Agents
- Doxycycline
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Topics |
- Animals
- Antiprotozoal Agents
(therapeutic use)
- Babesiosis
(physiopathology, prevention & control)
- Body Temperature
- Dogs
- Doxycycline
(therapeutic use)
- Female
- Fever
- Male
- Parasitemia
(physiopathology, prevention & control, veterinary)
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