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Prophylactic treatment of experimental canine babesiosis (Babesia canis) with doxycycline.

Abstract
Doxycycline provided satisfactory prophylaxis against experimental infection with a highly pathogenic strain of Babesia canis. Rectal temperature, parasitaemia, packed cell volume and serology were monitored for evaluation of the prophylactic effect. Although a daily dose of 5 mg kg-1 of doxycycline did not completely prevent clinical disease, symptoms remained moderate and a full recovery was obtained within 1 week. At a dose of 20 mg kg-1 day-1 no clinical symptoms were observed, but asymptomatic infection could not be ruled out.
AuthorsF Vercammen, R De Deken, L Maes
JournalVeterinary parasitology (Vet Parasitol) Vol. 66 Issue 3-4 Pg. 251-5 (Nov 15 1996) ISSN: 0304-4017 [Print] Netherlands
PMID9017887 (Publication Type: Journal Article)
Chemical References
  • Antiprotozoal Agents
  • Doxycycline
Topics
  • Animals
  • Antiprotozoal Agents (therapeutic use)
  • Babesiosis (physiopathology, prevention & control)
  • Body Temperature
  • Dogs
  • Doxycycline (therapeutic use)
  • Female
  • Fever
  • Male
  • Parasitemia (physiopathology, prevention & control, veterinary)

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