Lung transplantation for alpha 1-antitrypsin deficiency emphysema.

Abstract

Lung transplantation is an option for appropriately selected patients with end-stage emphysema caused by alpha 1-antitrypsin deficiency. The functional results have been excellent after single or bilateral lung transplantation, and the medium-term survival results have been good. However, the role of alpha 1-antitrypsin replacement therapy after lung transplantation remains uncertain, and further investigation is needed.

• Authors: E P Trulock
• Journal: Chest (Chest) Vol. 110 Issue 6 Suppl Pg. 284S-294S (Dec 1996) ISSN: 0012-3692 [Print] United States
• PMID: 8989166 (Publication Type: Journal Article, Review)

Chemical References

• Recombinant Proteins
• alpha 1-Antitrypsin

Topics

• Humans
• Lung Diseases, Obstructive (surgery)
• Lung Transplantation (mortality, statistics & numerical data)
• Pulmonary Emphysema (mortality, physiopathology, surgery)
• Recombinant Proteins (therapeutic use)
• Registries
• Respiratory Function Tests
• Survival Rate
• United States
• alpha 1-Antitrypsin (biosynthesis, therapeutic use)
• alpha 1-Antitrypsin Deficiency