[Uridine diphosphate sugar in meningiomas of the brain].

Abstract

The content of uridine-diphosphate (UDP)-saccharides, such as UDP-glucose (UDPG) and UDP-N-acetylglucosamine (UDPAG) was examined in the meningiomas obtained at surgery. Typical, atypical, and anaplastic meningiomas were used. Biochemical data were compared with histological findings. The total level of UDP-saccharides (UDPG + UDPAG) in the meningiomas was demonstrated not to depend on the grade of anaplasia. A positive correlation was found between the UDPG/UDPAG ratio was from 1.73 in typical (benign) neoplasms to 6 or even higher in meningiomas with severe sings of malignancy (anaplastic meningiomas). The UDPG/UDPAG ratio seems to reflect the nature and rate of tumor growth.

• Authors: G M Popova, M Sh Promyslov, G A Gabibov
• Journal: Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko (Zh Vopr Neirokhir Im N N Burdenko) 1996 Jul-Sep Issue 3 Pg. 30-1 ISSN: 0042-8817 [Print] Russia (Federation)
• Vernacular Title: Uridindifosfatsakhara v meningiomakh golovnogo mozga.
• PMID: 8975513 (Publication Type: English Abstract, Journal Article)

Chemical References

• Uridine Diphosphate Sugars

Topics

• Anaplasia (chemistry)
• Brain (pathology)
• Brain Chemistry
• Brain Neoplasms (chemistry)
• Humans
• Meningeal Neoplasms (chemistry)
• Meningioma (chemistry)
• Uridine Diphosphate Sugars (analysis)