Abstract |
This brief clinical report illustrates the case of a 50-y-old male patient with severe radiation-induced renal and intestinal fibrosis who received glutamine-enriched total parenteral nutrition (TPN). The patient had end-stage renal disease and, therefore, underwent a kidney transplant. In the postoperative course the patient developed signs of bowel obstruction and cachexia. He received two courses of glutamine-enriched TPN before he underwent surgery for small bowel stenosis. Postoperatively, the patient received a third course of glutamine-enriched TPN. During the patient's hospital course the following indexes were monitored: patient's weight, serum concentrations of protein, albumin, and trialglycerol. Intestinal permeability was assessed with the lactulose- mannitol sugar test (L-M test). We measured changes in the patient's weight and the L-M test. We hypothesize that glutamine-enriched TPN may have been beneficial in the hospital course of this critically ill patient and may have influenced the patient's intestinal function and permeability.
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Authors | C Wicke, T Gottwald, H D Becker |
Journal | Nutrition (Burbank, Los Angeles County, Calif.)
(Nutrition)
1996 Nov-Dec
Vol. 12
Issue 11-12 Suppl
Pg. S85-6
ISSN: 0899-9007 [Print] United States |
PMID | 8974127
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Fibrosis
- Glutamine
(administration & dosage)
- Humans
- Intestines
(pathology, radiation effects)
- Kidney
(pathology, radiation effects)
- Kidney Failure, Chronic
(surgery)
- Kidney Transplantation
- Male
- Middle Aged
- Parenteral Nutrition, Total
- Radiation Injuries
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