Abstract | BACKGROUND: OBSERVATIONS: Two brothers with Kindler syndrome had a history of primarily acral blistering since infancy as well as photosensitivity. Blister formation was found through the basal layer. Marked tonofilament clumping was found in intact keratinocytes adjacent to the blisters. The younger brother (aged 21 years) had actinic keratoses, which have not been previously described in Kindler syndrome. CONCLUSIONS:
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Authors | R M Haber, W M Hanna |
Journal | Archives of dermatology
(Arch Dermatol)
Vol. 132
Issue 12
Pg. 1487-90
(Dec 1996)
ISSN: 0003-987X [Print] United States |
PMID | 8961879
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Adult
- Blister
(pathology)
- Epidermolysis Bullosa
(genetics, pathology)
- Humans
- Intermediate Filaments
(ultrastructure)
- Keratinocytes
(pathology, ultrastructure)
- Keratins
- Keratosis
(pathology)
- Male
- Photosensitivity Disorders
(genetics, pathology)
- Rothmund-Thomson Syndrome
(genetics, pathology)
- Skin
(pathology, ultrastructure)
- Syndrome
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