Abstract | INTRODUCTION: The objective of this study was to evaluate the efficacy of thalidomide in the treatment of chronic erythema multiforme unresponsive to usual treatments. PATIENTS AND METHODS: RESULTS: Twenty patients had recurrent erythema multiforme and were given thalidomide at the beginning of an episode. The duration of the episodes was reduced by 11 days on the average. Six of the patients had subintrant erythema multiforme and were given continuous treatment. Lesions disappeared within 5 to 8 days and remission was maintained with low dose-treatment. DISCUSSION: The spectacular results obtained here should be verified in a controlled study.
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Authors | K Cherouati, A Claudy, P Souteyrand, F Cambazard, L Vaillant, G Moulin, B Crickx, P Morel, A Lamorelle, J Revuz |
Journal | Annales de dermatologie et de venereologie
(Ann Dermatol Venereol)
Vol. 123
Issue 6-7
Pg. 375-7
( 1996)
ISSN: 0151-9638 [Print] France |
Vernacular Title | Traitement par thalidomide, de l'érythème polymorphe chronique formes récidivantes et subintrantes. Etude rétrospective de 26 malades. |
PMID | 8959059
(Publication Type: English Abstract, Journal Article, Multicenter Study)
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Chemical References |
- Immunosuppressive Agents
- Thalidomide
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Topics |
- Adolescent
- Adult
- Aged
- Chronic Disease
- Erythema Multiforme
(drug therapy)
- Female
- Humans
- Immunosuppressive Agents
(therapeutic use)
- Male
- Middle Aged
- Recurrence
- Retrospective Studies
- Thalidomide
(therapeutic use)
- Treatment Outcome
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