Abstract | BACKGROUND: METHODS: We studied the records of 100 patients with chromaffin tumors who underwent abdominal exploration. The disease was familial in 28 patients and was malignant in 19. Seventy-five patients had intraadrenal disease (bilateral in 13). Computed tomography (CT), metaiodobenzylguanidine ( MIBG) scintigraphy, and magnetic resonance imaging (MRI) were performed since 1979, 1984, and 1987 in 97, 73, and 43 patients, respectively. False-positive and false-negative results were defined as any discrepancy between imaging results and surgical findings. RESULTS: Overall accuracy of preoperative localization was 85% with CT scan, 77% with MIBG scintigraphy, and 86% with MRI. In unilateral pheochromocytoma, accuracy was 94% with CT scan, 80% with MIBG scintigraphy, and 96% with MRI. When all three studies were performed (n = 38), overall accuracy was 97% and only one extraadrenal tumor in a patient with familial pheochromocytoma was overlooked. CONCLUSIONS: The outstanding accuracy of available imaging techniques questions the strategy of routine laparotomy for sporadic and seemingly benign pheochromocytomas, favoring more elective approaches such as the posterior approach or laparoscopy.
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Authors | F N Pattou, F P Combemale, J F Poirette, B Carnaille, J L Wemeau, D Huglo, O Ernst, C A Proye |
Journal | Surgery
(Surgery)
Vol. 120
Issue 6
Pg. 1006-11; discussion 1012
(Dec 1996)
ISSN: 0039-6060 [Print] United States |
PMID | 8957487
(Publication Type: Journal Article)
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Chemical References |
- Contrast Media
- Iodobenzenes
- 3-Iodobenzylguanidine
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Topics |
- 3-Iodobenzylguanidine
- Abdominal Neoplasms
(diagnosis, surgery)
- Adolescent
- Adrenal Gland Neoplasms
(diagnosis, surgery)
- Adult
- Aged
- Aged, 80 and over
- Child
- Child, Preschool
- Contrast Media
- Evaluation Studies as Topic
- Female
- Humans
- Iodobenzenes
- Laparotomy
- Magnetic Resonance Imaging
- Male
- Middle Aged
- Paraganglioma
(diagnosis, surgery)
- Pheochromocytoma
(diagnosis, surgery)
- Radionuclide Imaging
- Tomography, X-Ray Computed
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