Arylsulfonate esters of fatty alcohols as hypocholesterolemic agents. I: Oleyl and linoleyl p-toluenesulfonates.

Abstract	Cholesterol levels of both plasma and liver of cholesterol-fed rats are lowered by feeding linoleyl and oleyl esters of p-toluenesulfonic acid. A structural specificity exists, since the effect is not observed with similar amounts of sodium p-toluenesulfonate nor with linoleyl methanesulfonate. Effective levels of these arylsulfonates do not alter liver to body weight ratios and maturation, nor reduce plasma cholesterol in normocholesterolemic rats.
Authors	F W Quackenbush, P G Rand, J E MacNintch
Journal	Lipids (Lipids) Vol. 12 Issue 8 Pg. 686-8 (Aug 1977) ISSN: 0024-4201 [Print] United States
PMID	895419 (Publication Type: Journal Article)
Chemical References	Anticholesteremic Agents Cholesterol, Dietary Dietary Fats Linoleic Acids Oils Oleic Acids Tosyl Compounds
Topics	Animals Anticholesteremic Agents Cholesterol, Dietary Dietary Fats Drug Evaluation, Preclinical Hypercholesterolemia (drug therapy) Linoleic Acids (therapeutic use) Male Oils Oleic Acids (therapeutic use) Rats Tosyl Compounds (therapeutic use)

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